INSTENON IN THERAPY OF ACUTE CEREBROVASCU LAR DISORDERS

Effectiveness of Instenon (Alkaloid Pharm. Co.), the preparation, cont aining hexobendin, hydroxytheophyllin, etamivan was investigated in tr eatment of patients with acute cerebrovascular disorders. Instenon was applied in acute phase of ischemic stroke both in form of ampules and dragee as well as for intravenous injections too. Marked positive inf luence of instenon was observed on motor, sensory, autonomic and psych ic functions. Instenon in form of ampules had advantage compared to dr agee form in terms of faster positive alterations onset Application of instenon in form of ampules was more effective in patients with disor ders of consciousness while usage of drug in the form of dragee was mo re effective in patients with cerebrovascular disorders in vertebro-ba silar system. The drug hadn't significant influence on systemic arteri al pressure either after single injection or long-termed treatment; th e mild hypotensive effect was observed after therapeutical session. Th e drug was well folerated by patients in both forms and hadn't any sid e effects. Them were no negative consequences of instenon interaction with other preparations. The conclusion was made about possibility of application of instenon for the treatment of ischemic stroke.