Lung volume reduction surgery (LVRS) offers the potential to improve lung f
unction, exercise tolerance, and quality of life for patients with advanced
emphysema. At present, the specific role of this procedure in the treatmen
t of advanced emphysema is a subject of ongoing investigation. LVRS is most
commonly performed bilaterally via either median sternotomy or video thora
coscopic approach with resection of the most severely affected lung tissue
to reduce the overall lung volume by 20-30%. This results in improvements i
n lung elastic recoil, airway conductance, chest wall, and diaphragmatic fu
nction leading to greater inspiratory and expiratory airflow decreased hype
rinflation, and improved exercise tolerance. The greatest improvement after
LVRS occurs within 3-6 months after surgery In the perioperative period, h
owever lung function may be compromised by surgical incisions, pain, chest
tubes, retained secretions, pneumonia, and parenchymal injury associated wi
th resection. The risks of LVRS are not insignificant, with reported mortal
ity prior to hospital discharge ranging from 2.5 to 14%. Pulmonary complica
tions may include respiratory failure, persistent air leaks, pneumonia, tra
cheobronchitis, retained secretions, atelectasis, pneumothorax, bleeding, a
nd sternal wound infections or dehiscence. Cardiac and gastrointestinal com
plications are the most common extrathoracic causes of perioperative morbid
ity after LVRS. Although many patients have an uneventful postoperative cou
rse, patients who experience complications frequently require prolonged mec
hanical ventilation and intensive care. Critical care practitioners must th
erefore be familiar with LVRS, its potential complications, and the ICU man
agement of LVRS patients.