Hyponatremia and hyperglycemia during cardiopulmonary bypass related to cardioplegia solution

Alterations of sodium and glucose concentration may result from disorders o f the normal regulatory mechanisms or from excessive intake of glucose, sod ium, or free water In children, hyponatremia most commonly results from exc essive free mater intake, frequently combined with inadequate sodium intake . The author reports a child who developed hyponatremia and hyperglycemia d uring cardiopulmonary bypass that was eventually attributed to the large vo lume of cardioplegia solution that was used. When excess free water adminis tration is suspected as the etiology of hyponatremia, all possible sources should be considered.