Palladium-catalyzed cross-benzannulation of amilzoenynes with diynes, highly regioselective synthesis of polysubstituted anilines

Authors
Saito, S Uchiyama, N Gevorgyan, V Yamamoto, Y
Citation
S. Saito et al., Palladium-catalyzed cross-benzannulation of amilzoenynes with diynes, highly regioselective synthesis of polysubstituted anilines, J ORG CHEM, 65(14), 2000, pp. 4338-4341
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263 → ACNP
Volume
65
Issue
14
Year of publication
2000
Pages
4338 - 4341
Database
ISI
SICI code
0022-3263(20000714)65:14<4338:PCOAWD>2.0.ZU;2-T
Abstract
Polysubstituted anilines were prepared by the palladium-catalyzed cross-ben zannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proce eded in a highly regioselective manner under mild conditions, and the anili nes were obtained as single regioisomers. Our method complements the well-k nown precedures for the preparation of polysubstituted anilines which are w idely used in organic synthesis.