Kinetic resolution in Pd-catalyzed allylic substitution using the helical PHelix ligand

Authors
Reetz, MT Sostmann, S
Citation
Mt. Reetz et S. Sostmann, Kinetic resolution in Pd-catalyzed allylic substitution using the helical PHelix ligand, J ORGMET CH, 603(1), 2000, pp. 105-109
Citations number
30
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANOMETALLIC CHEMISTRY
ISSN journal
0022328X → ACNP
Volume
603
Issue
1
Year of publication
2000
Pages
105 - 109
Database
ISI
SICI code
0022-328X(20000522)603:1<105:KRIPAS>2.0.ZU;2-R
Abstract
The chiral helical diphosphine 2,1 5-bis(diphenylphosphino)-hexahelicene (P Helix) is an excellent ligand in palladium catalyzed kinetic resolution inv olving allylic substitution. Depending upon the substrate, enantioselectivi ties (ee) of up to 99% are observed. Although formally a diphosphine, PHeli x appears not to undergo chelation, which means that it behaves as a chiral monophosphine. (C) 2000 Published by Elsevier Science S.A. All rights rese rved.