The application of Pd-complexes of diphenylphosphinoferrocenyloxazoline ligands to catalytic enantioselective allylic amination

Authors
Malone, YM Guiry, PJ
Citation
Ym. Malone et Pj. Guiry, The application of Pd-complexes of diphenylphosphinoferrocenyloxazoline ligands to catalytic enantioselective allylic amination, J ORGMET CH, 603(1), 2000, pp. 110-115
Citations number
33
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANOMETALLIC CHEMISTRY
ISSN journal
0022328X → ACNP
Volume
603
Issue
1
Year of publication
2000
Pages
110 - 115
Database
ISI
SICI code
0022-328X(20000522)603:1<110:TAOPOD>2.0.ZU;2-M
Abstract
The preparation of cationic palladium (eta(3)-C3H5) complexes, possessing a n enantiopure diphenylphosphinoferrocenyloxazoline unit, is described. Thes e complexes were applied to the enantioselective amination of the test subs trate, ethyl (2E)-1,3-diphenyl-prop-2-enyl carbonate, with benzylamine in m oderate to high conversions with enantioselectivities of up to 72% for the (S)-valinol derived oxazoline complex. Enantioselectivities of up to 37% we re obtained for the (S)-tert-leucinol derived oxazoline complex. (C) 2000 E lsevier Science S.A. All rights reserved.