P. Cortelli et al., A MULTINATIONAL INVESTIGATION OF THE IMPACT OF SUBCUTANEOUS SUMATRIPTAN .3. WORKPLACE PRODUCTIVITY AND NON-WORKPLACE ACTIVITY, PharmacoEconomics, 11, 1997, pp. 35-42
This report presents the workplace productivity and non-workplace acti
vity results of a multinational study of the effects of subcutaneous s
umatriptan 6mg in the acute treatment of migraine compared with patien
t's customary therapy. Patients diagnosed with migraine treated their
symptoms for 24 weeks with subcutaneous sumatriptan after a 12-week pe
riod of treating symptoms with their customary (non-sumatriptan) thera
py. Patients used diary cards to record information concerning the eff
ects of migraine on workplace productivity and non-workplace activity
time. The average workplace productivity time lost was 23.4 hours per
patient during 12 weeks of customary therapy, compared with 7.2 and 5.
8 hours per patient during the first and second 12-week periods of sum
atriptan therapy, respectively. An average of 9.3 hours of non-workpla
ce activity time was lost per patient during the customary therapy pha
se, compared with 3.2 and 2.8 hours during the first and second 12-wee
k periods of sumatriptan therapy, respectively. Treatment of migraine
with subcutaneous sumatriptan compared with customary therapy was asso
ciated with an average gain per patient of approximately 16 hours of w
orkplace productivity time and 6 hours of non-workplace activity time,
over a 3-month period.