Synthesis and spectroscopic properties of new phthalocyanine complexes with potentially combined photodynamic activity and cytotoxicity for photodynamic therapy

Authors
Nemykin, VN Mytsyk, VM Volkov, SV Kobayashi, N
Citation
Vn. Nemykin et al., Synthesis and spectroscopic properties of new phthalocyanine complexes with potentially combined photodynamic activity and cytotoxicity for photodynamic therapy, J PORPHYR P, 4(5), 2000, pp. 551-554
Citations number
16
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
ISSN journal
10884246 → ACNP
Volume
4
Issue
5
Year of publication
2000
Pages
551 - 554
Database
ISI
SICI code
1088-4246(200008)4:5<551:SASPON>2.0.ZU;2-Z
Abstract
The reaction of zinc tetrakis(3-pyridyloxy)phthalocyanine (I) with NH4[PtNH 3Cl3] leads to zinc tetrakis(cis-[3-oxypyridyl]-N] amminedichloroplatinum(I I))phthalocyanine (2), while the reaction of 1 with cis-Pt (DMSO)(2)Cl-2 or 2 with DMSO forms zinc tetrakis(cis-[(3-oxypyridyl)-N]dichloro[ (TT))phtha locyanine (3). The new phthalocyanines 2 and 3, with potentially combined p hotodynamic activity and cytotoxicity, have been characterized by means of electronic, H-1 NCR and IR spectroscopies. Copyright (C) 2000 John Wiley & Sons, Ltd.