Microfabrication technologies have made possible the development of meso-sc
ale energy conversion and chemical processing systems with microscale featu
res, Scaling effects, such as the linear increase in surface-area-to-volume
ratio that affects surface processes such as convection heat transfer, ads
orption, and catalytic chemical conversion processes, provide some of the m
otivation for the miniaturization efforts. Other mechanical, thermal, and f
luid scaling effects are presented. Fabrication and material limitations, a
s well as scaling effects, must be considered in the design process and may
result in miniaturized systems that are considerably different than their
full-scale prototypes, System and component development efforts at Battelle
Pacific Northwest National Laboratories are highlighted. A fuel atomizer f
or gas turbine engines and a multicomponent fuel processor for the producti
on of on-demand hydrogen are microscale components that show potential for
improving current large-scale systems. Complete miniaturized systems such a
s a gas turbine, a vapor-absorption heat pump, and a Joule-Thompson cryocoo
ler could be used for mobile power production and cooling of electronics an
d individuals. Components for miniaturized systems include microbatteries w
ith multiple definable voltage levels and a high degree of integratability
and a combustor/evaporator for methane combustion with low levels of harmfu
l emissions.