Synthesis of platinum complexes from N-benzyl ethylenediamine derivatives

N-benzylethylenediamine derivatives have been prepared in good yields using methodology diferent than that described in the literature. H-1 and C-13 N MR spectra were used to characterize those compounds. Nine new platinum(II) complexes, analogs of cisplatin and carboplatin, containing these ligands have been prepared and characterized. Preliminary in vitro tests against bu ccal human carcinoma cell lines (KB cells) shouted that the complexes are c ytotoxic.