B. Moskovitz et al., GLUTAMINE-METABOLISM AND UTILIZATION - RELEVANCE TO MAJOR PROBLEMS INHEALTH-CARE, Pharmacological research, 30(1), 1994, pp. 61-71
Glutamine plays an important role in normal and pathophysiological sta
tes. In this review we describe the biochemical synthesis and degradat
ion pathways of glutamine, as well as its utilization by the immune sy
stem and in rapidly dividing cells. Also discussed are glutamine behav
iour in catabolic states and the therapeutic implications of this amin
o acid in total parenteral nutrition, digestive diseases and cancer.