We report a patient with a cerebral cryptococcal granuloma who presented wi
th recent memory disturbance and deteriorating mental status followed by te
mporary loss of consciousness. To our knowledge, this is the first report o
f a cerebral cryptococcal granuloma examined by a combination of convention
al MRI, fluid-attenuated inversion recovery and diffusion-weighted imaging
and in which the surgical specimen was analysed histochemically.