Multiply scattered light tomography and confocal imaging: detecting neovascularization in age-related macular degeneration

A novel technique, Multiply Scattered Light Tomography (MSLT), and confocal Infrared Imaging are used to provide diagnostic information using a comfor table, rapid, and noninvasive method. We investigated these techniques in d etecting neovascularization in age-related macular degeneration. The MSLT u sed a Vertical Cavity Surface Emitting Laser (VCSEL) at 850 nm, while the c onfocal imaging technique used either the VCSEL or a 790 nm laser diode. Bo th were implemented into the topographical scanning system (TopSS, Laser Di agnostic Technologies, Inc.) Confocal imaging with both lasers provided dif ferent information about neovascularization as a function of focal plane, a nd different also from MSLT. (C) 2000 Optical Society of America.