NEUROPSYCHOLOGICAL COURSE AFTER SURGERY FOR INTRACRANIAL ANEURYSMS - A PROSPECTIVE-STUDY AND A CRITICAL-REVIEW

Previously, only three studies with representative samples of patients with ruptured intracranial aneurysms have provided detailed results o f prospective, repeated, neuropsychological assessments after surgery. These studies apparently disagree with regard to occurrence of cognit ive deficits and to degree of improvement between early and delayed fo llow-ups. The present paper attempts to analyze the conditions underly ing these differences in results. As a first step in this analysis we present a comprehensive, prospective, neuropsychological investigation of a consecutive sample of 41 patients with rupture of a supratentori al aneurysm, assessed 4 and 12 months after surgery. It is concluded t hat a prorated course of improvement of a wide specter of psychologica l functions may be revealed, but that sensitive tests and large sample s are needed to establish the range of deficits and improvements with time. Differences in patient selection with respect to severity of the acute clinical state and delayed deterioration apparently contribute importantly to the discrepance in previously reported outcome.