POEMS syndrome - a case report

One rare case of POEMS syndrome is presented. In a 39-year-old male patient a progressive numbness in hands and feet developed within 5 years. Admissi on with increasing dyspoea and lower leg edema. In swollen inguinal lymph n odes a lymphadenopathia with angiofollicular hyperplasia and vascular-plasm acelluluar proliferation was diagnosed and classified as Castleman-like his tologic features. In os ilium an osteosclerotic plasmocytoma with restricti on of kappa light chains was found. Potential pathomechanism of POEMS syndr ome are discussed.