Reaction of organozinc compounds with cyanoalkylphosphonates: General method for synthesis of beta-, gamma- and delta-ketophosphonates

Authors
Harizi, A Hajjem, B Zantour, H Baccar, B
Citation
A. Harizi et al., Reaction of organozinc compounds with cyanoalkylphosphonates: General method for synthesis of beta-, gamma- and delta-ketophosphonates, PHOSPHOR SU, 159, 2000, pp. 37-46
Citations number
28
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
ISSN journal
10426507 → ACNP
Volume
159
Year of publication
2000
Pages
37 - 46
Database
ISI
SICI code
1042-6507(2000)159:<37:ROOCWC>2.0.ZU;2-S
Abstract
In recent years phosphorylated ketones were considered as valuable intermed iates in organic synthesis. In the present work we studied the reaction of cyanoalkylphosphonates 1 with organozinc compounds which led after hydrolys is to the corresponding phosphorylated ketones 2 and 3. The structure of th ese products was confirmed by IR and NMR (IH, C-13, P-31) spectroscopy.