Recent investigations in magnetic resonance imaging in animals and human su
bjects have demonstrated that laser polarized helium-3 can be used to visua
lize airways and air spaces. This report presents the current performances
and possible improvements of optical pumping techniques for the production
of polarized gas. The specific properties and dynamics of the polarization
inside the lungs am also discussed. They impact both the development of opt
imal imaging methods and the analysis of the data to extract physiological
information. Applications to medical assessment of lung ventilation and fun
ction are considered.