Objective: This study was undertaken to determine the relative shear bond s
trengths and microleakage of 4 bonding agents to dentin and amalgam and to
investigate the bonding to dentin through confocal laser scanning microscop
y. Method and materials: Sixty noncarious molars were restored with 1 of 4
different systems, and the shear bond strengths were determined. For the mi
croleakage study, Class V amalgam restorations were placed in 60 noncarious
teeth. The specimens were thermocycled, the teeth were sectioned, and dye
penetration was assessed. For confocal examinations, the first component of
the bonding adhesives was labeled with rhodamine B. Each of the adhesives
was applied to 3 dentin specimens, which were examined under a confocal las
er scanning microscope. Results: Of the 4 restorative systems tested, Amalg
amBond Plus + HPA and Prime & Bond 2.1/base-catalyst showed significantly h
igher shear bond strengths. Prime & Bond 2.1/base-catalyst had the lowest m
icroleakage value, which was significantly lower than that of AmalgamBond P
lus + HPA and AmalgamBond Plus. AmalgamBond Plus + HPA had the highest vari
ation in both the bond strength and microleakage values. Confocal laser sca
nning microscopy revealed tag formation, penetration of the bonding agents
deep into the tubules, and hybrid layer formation for all 4 bonding systems
. Conclusion: The 2 best systems, Prime & Bond 2.1/base-catalyst and, to a
lesser extent, AmalgamBond Plus + HPA, utilized a supplemental bonding agen
t.