The objective was to evaluate whether activity of radon progenies can be de
tected in sweat following speleotherapeutic radon exposure (40 kBq/m(3)) in
a warm (38 degrees C) and humid (relative humidity >70%) environment. A gr
oup of 11 male patients with spondyloarthropathy (n=6) or non-inflammatory
rheumatic diseases (n=5) underwent a 1-h treatment in the gallery of the Ga
steiner Heilstollen, and 20 min after leaving the treatment area radon prog
eny activity was measured in sweat by utilizing a special filter set. The r
esults suggest that radon is discharged with sweat, causing a significant a
ctivity of radon and radon progenies on the skin. This finding may be impor
tant from a clinical point of view, since specialists experienced in radon
therapy have repeatedly emphasized the importance of the degree of radioact
ivity on the skin for the effectiveness of treatment. It has even been clai
med that the skin is the major target for radon therapy, possibly because o
f the influence on Langerhans' cell function.