Jc. Williams et al., Giant cell reparative granuloma of the petrous temporal bone: A case report and literature review, SKULL BAS S, 10(2), 2000, pp. 89-93
Giant cell reparative granuloma (GCRG) is an unusual, benign bone lesion th
at most commonly affects the maxilla and mandible; skull involvement is rar
e. The etiology is uncertain but may be related to trauma. GCRG is difficul
t to distinguish from giant cell tumor of the bone and has a lower recurren
ce rate. Thirteen reports of temporal bone GCRG in 11 patients have been re
ported. One report of a petrous GCRG in a 3-year-old girl has been identifi
ed. A 38-year-old male presented with a 2-year history of fullness in his l
eft ear, ipsilateral hearing loss, and intermittent cacosmia. Computed tomo
graphy and magnetic resonance imaging revealed a large left-sided anterior
temporal extradural mass. The patient underwent a left frontotemporal crani
otomy and resection of a left temporal fossa turner that involved the petro
us and squamous parts of the temporal bone. The patient's post-operative co
urse was uneventful, except for increased hearing loss secondary to opening
of the epitympanum. Follow-up at one month revealed no other problems. His
topathology of the specimen was consistent with a giant cell reparative gra
nuloma.