High-field NMR studies of 3 beta-tetrahydropyranyloxy steroids

Authors
Szendi, Z Forgo, P Kover, KE Sweet, F
Citation
Z. Szendi et al., High-field NMR studies of 3 beta-tetrahydropyranyloxy steroids, STEROIDS, 65(7), 2000, pp. 415-422
Citations number
19
Categorie Soggetti
Biochemistry & Biophysics
Journal title
STEROIDS
ISSN journal
0039128X → ACNP
Volume
65
Issue
7
Year of publication
2000
Pages
415 - 422
Database
ISI
SICI code
0039-128X(200007)65:7<415:HNSO3B>2.0.ZU;2-J
Abstract
Comprehensive NMR studies were carried out on 3 beta-hydroxy-pregnene and c holestene analogs, each containing a tetrahydropyranyl ether group at the 3 -position. Two-dimensional NMR experiments (COSY, TOCSY, HSQC, and HSQC-TOC SY) permitted the complete assignments of both the H-1 and C-13 resonances of these derivatives in deuterated benzene or chloroform. The aromatic solv ent-induced NMR signal shifts (ASIS) were also investigated. (C) 2000 Elsev ier Science Inc. All rights reserved.