Facile synthesis of 3,4-dihydroxyprolines as an application of the L-threonine aldolase-catalyzed aldol reaction

Authors
Fujii, M Miura, T Kajimoto, T Ida, Y
Citation
M. Fujii et al., Facile synthesis of 3,4-dihydroxyprolines as an application of the L-threonine aldolase-catalyzed aldol reaction, SYNLETT, (7), 2000, pp. 1046-1048
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
7
Year of publication
2000
Pages
1046 - 1048
Database
ISI
SICI code
0936-5214(200007):7<1046:FSO3AA>2.0.ZU;2-A
Abstract
A new facile synthesis of 3,4-dihydroxyprolines was attained by taking adva ntage of the L-threonine aldolase, which catalyzes the aldol condensation r eaction of aldehydes with glycine affording beta-hydroxy-alpha-L-amino acid s.