Epidural drug administration is a technique that allows analgesic agents to
be administered in close proximity to their site of action. This technique
provides profound, long-lasting analgesia with minimal adverse effects bec
ause lower drug doses are generally used compared with systemic administrat
ion. Local anesthetics placed epidurally can produce complete desensitizati
on and muscle relaxation to the kind end. The technique requires minimal eq
uipment and is easily learned. Local anesthetic agents, opioids, and their
combination can provide moderate to excellent intraoperative analgesia and
up to 24 hours of postoperative analgesia.