Dynamics of lip dyskinesia associated with neuroleptic withdrawal

The Lip movements associated with dyskinesia in adults with mental retardat ion were investigated through a dynamic analysis at medication baseline, at the points of the highest level of withdrawal dyskinesia as indexed by the DISCUS rating scale, and at the lowest level of dyskinesia following compl ete withdrawal of the medication. Results showed that the changes in the am ount of lip oscillations following medication reduction and eventual withdr awal were strongly Linked to changes in the structural complexity of the dy namics of lip motions. These findings provide evidence that neuroleptic med ication reduces the df of the dynamics of the movement output and that this change is inversely related to the level of tardive dyskinetic motion obse rved in the clinical setting.