The activity of MK-826 was compared to the activities of cefoxitin, ceftria
xone, imipenem, and meropenem against 363 gram-negative and gram-positive a
naerobes by using NCCLS procedures. At least 98% of the strains were suscep
tible to the carbapenems. All strains of Clostridium perfringens, Fusobacte
rium nucleatum, Peptostreptococcus, and Sutterella wadsworthensis were susc
eptible to all agents tested.