In vitro activities of the glycylcycline GAR-936 against gram-positive bacteria

Authors
Boucher, HW Wennersten, CB Eliopoulos, GM
Citation
Hw. Boucher et al., In vitro activities of the glycylcycline GAR-936 against gram-positive bacteria, ANTIM AG CH, 44(8), 2000, pp. 2225-2229
Citations number
16
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
8
Year of publication
2000
Pages
2225 - 2229
Database
ISI
SICI code
0066-4804(200008)44:8<2225:IVAOTG>2.0.ZU;2-Q
Abstract
The in vitro activities of GAR-936, the 9-t-butylglycylamido derivative of minocycline, were compared with those of doxycycline, minocycline, acid tet racycline against 527 gram-positive clinical isolates. GAR-936 inhibited al l strains, including those resistant to other tetracyclines, at concentrati ons of less than or equal to 2 mu g/ml, except two strains of JE; diphthero ids for which the MIC was 4 mu g/ml.