Solid-phase synthesis of an arylsulfone hydroxamate library

Authors
Salvino, JM Mathew, R Kiesow, T Narensingh, R Mason, HJ Dodd, A Groneberg, R Burns, CJ McGeehan, G Kline, J Orton, E Tang, SY Morrisette, M Labaudininiere, R
Citation
Jm. Salvino et al., Solid-phase synthesis of an arylsulfone hydroxamate library, BIOORG MED, 10(15), 2000, pp. 1637-1640
Citations number
10
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
15
Year of publication
2000
Pages
1637 - 1640
Database
ISI
SICI code
0960-894X(20000807)10:15<1637:SSOAAH>2.0.ZU;2-4
Abstract
Synthesis of an arylsulfone hydroxamate lead optimization library is presen ted. Biological activity of representative examples is given to demonstrate the value of this approach for lead optimization. (C) 2000 Elsevier Scienc e Ltd. All rights reserved.