Synthesis of aminophosphonate haptens for an aminoacylation reaction between methyl glucoside and a beta-alanyl ester

Authors
Lintunen, T Yli-Kauhaluoma, JT
Citation
T. Lintunen et Jt. Yli-kauhaluoma, Synthesis of aminophosphonate haptens for an aminoacylation reaction between methyl glucoside and a beta-alanyl ester, BIOORG MED, 10(15), 2000, pp. 1749-1750
Citations number
10
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
15
Year of publication
2000
Pages
1749 - 1750
Database
ISI
SICI code
0960-894X(20000807)10:15<1749:SOAHFA>2.0.ZU;2-J
Abstract
Two 2-aminophosphonate haptens derived from methyl alpha-D-glucopyranoside were synthesized to mimic the transition-state of a transesterification rea ction between methyl alpha-D-glucopyranoside and 3-nitrophenylester of tert -BOC-beta-alanine. Two sets of monoclonal antibodies were generated against these haptens. (C) 2000 Elsevier Science Ltd. All rights reserved.