Chiral recognition of diketopiperazines with xanthone receptors

Authors
Martin, M Raposo, C Oliva, AI Simon, L Caballero, C Moran, JR
Citation
M. Martin et al., Chiral recognition of diketopiperazines with xanthone receptors, CHEM LETT, (7), 2000, pp. 718-719
Citations number
14
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
7
Year of publication
2000
Pages
718 - 719
Database
ISI
SICI code
0366-7022(20000705):7<718:CRODWX>2.0.ZU;2-N
Abstract
Good chiral recognition of diketopiperazines has been obtained with a recep tor that combines a xanthone with a phosphonamide as an asymmetric group. S ilicagel plates impregnated with an enantiomerically pure diketopiperazine provide an easy and effective way to resolve the receptor racemic mixture. The strong (R,R. R) complex yields a spot with a larger R-f probably becaus e the complex is less polar than the free receptor.