Citation
Yc. Tang et al., Synthesis of cyclopentapeptides using an organophosphorus reagent DEPBT, CHEM LETT, (7), 2000, pp. 826-827
Citations number
7
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022
→ ACNP
Issue
7
Year of publication
2000
Pages
826 - 827
Database
ISI
SICI code
0366-7022(20000705):7<826:SOCUAO>2.0.ZU;2-O
Abstract
Two cyclopentapeptides cyclo(ProTyrLeuAlaGly)(1) and cyclo(AlaTyrLeuAlaGly)
(2) isolated and identified from a Chinese medicinal herb were chosen as mo
del cyclopeptides to evaluate a novel coupling reagent DEPBT (3-(diethoxy-p
hosphoryloxy-1,2,3-benzotriazin-4(3H)-one). DEPBT was used for synthesis of
cyclic peptides in one-pot procedure. Compared with some other coupling re
agents, the cyclization yields were satisfactory.