Present issues in the determination of troponins and other markers of cardiac damage

Objective: To review some of the recently proposed improvements and the cor responding apparent issues in the field of biochemical markers of cardiac d amage. Conclusions: The continuous development of new analytical tools for the bio chemical evaluation of patients with suspected myocardial injury brings wit hout doubt new challenges of careful technological evaluation, implementati on, and standardization but it may also provide a unique opportunity to mar kedly enhance our diagnostic performance in the clinical setting of acute c oronary syndrome. Copyright (C) 2000 The Canadian Society of Clinical Chemi sts.