Anti-cancer activity studies of indolalthiohydantoin (PIT) on certain cancer cell lines

Authors
Suzen, S Buyukbingol, E
Citation
S. Suzen et E. Buyukbingol, Anti-cancer activity studies of indolalthiohydantoin (PIT) on certain cancer cell lines, FARMACO, 55(4), 2000, pp. 246-248
Citations number
18
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
55
Issue
4
Year of publication
2000
Pages
246 - 248
Database
ISI
SICI code
0014-827X(200004)55:4<246:AASOI(>2.0.ZU;2-I
Abstract
5-(2-Phenyl-3'-indolal)-2-thiohydantoin (PIT) has been evaluated as an anti -cancer compound on several cancer lines organised in to subpanels represen ting leukemia, melanoma, and cancer of lung, colon, kidney, ovary, breast, prostate and central nervous system by the National Cancer Institute (NCI) anti-cancer drug screen programme. The compound showed inhibitory activity on several cancer cell lines. No information is available on anti-cancer po tency of this compound with normal cell lines. (C) 2000 Elsevier Science S. A. All rights reserved.