Immunosuppressed organ transplant recipients have an increased risk of deve
loping lymphoproliferative disorders that are often associated with Epstein
-Barr virus (EBV) infection. We report the case of a pacient who developed
multiple myeloma after renal transplantation. EBV-RNA was demonstrated in t
he neoplastic cells suggesting the implication of this virus genome in the
pathogenesis of this post-transplantation lymphoproliferative disorder.