The results of a feasibility study for a high-resolution PET detector syste
m are presented. The detector is based on the use of etched LSO scintillati
on crystals viewed from just one end. We have demonstrated that this config
uration yields Depth-of-Interaction (DOI) information whilst also preservin
g good energy and coincidence-time resolution. A prototype detector was bui
lt using a 4x4 crystal array coupled to 61-pixel hybrid photodiodes. The me
asurements demonstrate a. DOI resolution of 5 similar to 7mm FWHM in a 30mm
deep detector. The signal level was measured to be in the range 250 to 600
photoelectrons depending on the location of the 511 keV energy deposit in
the crystal. A resolving-time of less than 5ns FWHM was estimated based on
indirect measurements. The technique depends on the assumption that all of
the events detected above a selected threshold value are, in fact, full-ene
rgy deposits. The validity of this assumption and the impact of the photons
scattered in the object have been studied using a Monte Carlo simulation o
f the proposed small animal PET imager.