Objectives: This study compared the relative cost-effectiveness of stroke c
are provided in London and Copenhagen.
Methods: Hospitalized stroke patients at centers in London (1995-96) and Co
penhagen (1994-95) were included. Each patient's use of hospital and commun
ity health services was recorded for 1 year after stroke. Center-specific u
nit costs were collected and converted into dollars using the Purchasing Po
wer Parity Index. An incremental cost-effectiveness ratio (ICER) was calcul
ated comparing a Copenhagen model of stroke care to a London model, using r
egression analysis to adjust far case-mix differences.
Results: A total of 625 patients (297 in Copenhagen, 328 in London) were in
cluded in the analysis. Most patients in London (85%) were admitted to gene
ral medical wards, with 26% subsequently transferred to a stroke unit. In C
openhagen, 57% of patients were directly admitted to a stroke or neurology
unit, with 23% then transferred to a separate rehabilitation hospital. The
average length of total hospital stay was 11 days longer in Copenhagen. Pat
ients in Copenhagen were less likely to die than those in London; for patie
nts with cerebral infarction the hazard ratio after case-mix adjustment was
0.53 (95% CI from 0.35 to 0.80). However, a lower proportion of patients w
ith hemorrhagic stroke died in London. The ICER of using the Copenhagen com
pared with the London model of care ranged from $21,579 to $37,444 per life
-year gained for patients with cerebral infarctions.
Conclusions: The ICERs of the Copenhagen compared with the London model of
care were within a range generally regarded as cost-effective.