A construction worker with rheumatoid arthritis presented with multiple sof
t tissue masses on the volar surface of the palm and digits. A misdiagnosis
of rheumatoid nodules was made secondary to the patient's history of rheum
atoid arthritis. Subsequent excision confirmed multiple epidermal inclusion
cysts, which was not entertained in the preoperative differential diagnosi
s. Follow-up evaluation 3 years later revealed no evidence of local recurre
nce. Based on our literature review, multiple epidermal inclusion cysts is
a rare entity and has not been reported in a patient with rheumatoid arthri
tis. (J Hand Surg 2000;25A:768-771. Copyright (C) 2000 by the American Soci
ety for Surgery of the Hand).