A parallel study was conducted on two Indo-Pacific foliose sponges, Th
e first specimen contains 3-hydroxy-20,22-dimethyl-20-deoxoscalarin (2
), while the second contains 3-oxo-20,22-dimethyl-20-dioxoscalarin 8 (
3). The physical properties as well as X-ray results confirming the st
ructure and stereochemical features of these compounds are presented f
irst. The difficulty we encountered in the taxonomic identification of
these species is also discussed, One of our specimens rs identical to
material considered by different taxonomists as either Phyllospongia
vermicularis or Dysidea vermicularis, The other is identified as Carte
riospongia sp. We outline that the parallel chemistry of these two spe
cimens suggests that they are closely related taxonomically.