ANTIHYPERGLYCEMIC ACTIVITY OF PHENOLICS FROM PTEROCARPUS-MARSUPIUM

Authors
MANICKAM M RAMANATHAN M JAHROMI MAF CHANSOURIA JPN RAY AB
Citation
M. Manickam et al., ANTIHYPERGLYCEMIC ACTIVITY OF PHENOLICS FROM PTEROCARPUS-MARSUPIUM, Journal of natural products, 60(6), 1997, pp. 609-610
Citations number
21
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
60
Issue
6
Year of publication
1997
Pages
609 - 610
Database
ISI
SICI code
0163-3864(1997)60:6<609:AAOPFP>2.0.ZU;2-F
Abstract
Glucose levels in rats with hyperglycemia induced by streptozotocin we re determined after ip administration of marsupsin (1), pterosupin (2) , and pterostilbene (3), three important phenolic constituents of the heartwood of Pterocarpus marsupium. Marsupsin and pterostilbene signif icantly lowered the blood glucose level of hyperglycemic rats, and the effect was comparable to that of 1,1-dimethylbiguanide (metformin).