PROTEIN-FOLDING - DOES DIFFUSION DETERMINE THE FOLDING RATE

Authors
Citation
Te. Creighton, PROTEIN-FOLDING - DOES DIFFUSION DETERMINE THE FOLDING RATE, Current biology, 7(6), 1997, pp. 380-383
Citations number
18
Categorie Soggetti
Biology,Biology
Journal title
ISSN journal
09609822
Volume
7
Issue
6
Year of publication
1997
Pages
380 - 383
Database
ISI
SICI code
0960-9822(1997)7:6<380:P-DDDT>2.0.ZU;2-Z
Abstract
A major question about protein folding is whether the coming together by diffusion of different segments of the polypeptide chain is rate-de termining. This seemingly simple question has been very difficult to a nswer experimentally, but a positive result has now been obtained with one small model protein.