Qw. Li et al., Immobilization of glucose oxidase in sol-gel matrix and its application tofabricate chemiluminescent glucose sensor, MAT SCI E C, 11(1), 2000, pp. 67-70
In this paper, glucose oxidase (GOD) was immobilized in the course of sol-g
el process of TEOS, and we cast the GOD-doped sol to different supports (si
lica gel and molecular sieve) to prepare the GOD columns. It was demonstrat
ed that the activity of GOD remained high in sol-gel matrix. With the appli
cation of the GOD column prepared with sol-gel method to a flowing injectio
n chemiluminescent system, glucose could be effectively determined with the
linear range of the concentration in 3.5-70 mu mol/l and the detection Lim
it was at 0.6 mu mol/l. (C) 2000 Elsevier Science S.A. All rights reserved.