S. Ledru et Jp. Canonne, Epidemiologic follow-up of multi-drug resistant bacteria by the Laboratoryof Microbiology in a general hospital in Lens, France., MED MAL INF, 29(8), 1999, pp. 508-515
Objectives - For the last few years, follow-up of multiresistant bacteria a
nd hospital-acquired infections has become mandatory in hospital environmen
ts. Since April 1997, we have been testing an assessment procedure on multi
-drug resistant bacteria, based on data collected at the Microbiology Labor
atory.
Material and methods - We chose to assess regular incidence rather than pre
valence. The selected unit was the number of new colonizations or contamina
tion with a multiresistant bacteria for 1,000 patient days. Methicillin res
istant S. aureus (MRSA) extended broad spectrum lactamase Enterobacteriacea
e (EBSLE) P. aeruginosa resistant to ticarcillin, and A. baumannii were fir
st computerized because they were the most threatening species in our hospi
tal. However other species, such as Stenotrophomonas maltophilia or vancomy
cin resistant enterococci could be included later if infections occurred.
Results - From April 1997 to March 1998 the incidence of the different MDR
for the whole of the hospital was 0.94 parts per thousand for MRSA, 0.70 pa
rts per thousand for EBSLE, 1.12 parts per thousand for P. aeruginosa resis
tant to ticarcilline, and 0.68 parts per thousand for A. baumannii. The per
centage of resistance to methicillin for S. aureus, resistance to ticarcill
in for P. aeruginosa, and the percentage of secretion of EBSLE were also ca
lculated for various departments. In hospital we noted 26.4% of MRSA, 45.5%
of P. aeruginosa resistant to ticarcilline, 10.1% of EBS K. pneumoniae, an
d 38.6% of EBS E. aerogenes. (C) 1999 Elsevier, Paris.