Recurrent spontaneous abortion - Etiologic factors

Background. Spontaneous abortion is the most common complication of pregnan cy. It may be unique, remaining random and having no consequences on the re productive process, or it can repeat itself, starting a clinical picture kn own as recurrent spontaneous abortion or habitual abortion. The term of RSA syndrome is used to define the repetition of three or more consecutive abo rtions before the 24(th) week. Methods. A population of 195 couples with recurrent spontaneous abortion we re screened for genetic, metabolic, infective, morphological, endocrine and autoimmune factors, Eighty-five completed the investigation, 44 are being tested and 66 did not complete the diagnostic course. Causes of recurrent a bortion were evaluated in relation to the period of abortion and number of embryo losses. Results, Forty-six percent of patients who completed the investigation turn ed out to be sine causa, which is in accordance with the findings in litera ture. Conclusions. Couple with RSA require accurate counselling and it is fundame ntal to eliminate any pathologies that can be discovered so as to improve t he likelihood of the pregnancy's reaching term.