Decoys 'R' Us: A database of incorrect conformations to improve protein structure prediction

Authors
Samudrala, R Levitt, M
Citation
R. Samudrala et M. Levitt, Decoys 'R' Us: A database of incorrect conformations to improve protein structure prediction, PROTEIN SCI, 9(7), 2000, pp. 1399-1401
Citations number
14
Categorie Soggetti
Biochemistry & Biophysics
Journal title
PROTEIN SCIENCE
ISSN journal
09618368 → ACNP
Volume
9
Issue
7
Year of publication
2000
Pages
1399 - 1401
Database
ISI
SICI code
0961-8368(200007)9:7<1399:D'UADO>2.0.ZU;2-Y
Abstract
The development of an energy or scoring function for protein structure pred iction is greatly enhanced by testing the function on a set of computer-gen erated conformations (decoys) to determine whether it can readily distingui sh native-like conformations from nonnative ones. We have created "Decoys ' R' Us," a database containing many such sets of conformations, to provide a resource that allows scoring functions to be improved.