Invasive fungal infections are an increasingly common problem in patients w
ith cancer and other vulnerable groups. We report a case of hepatosplenic h
ialohifomycosis probably by Aspergillus sp. In a patient with acute leukemi
a, and prolonged neutropenia, treated with corticosteroids and broad spectr
um antibiotics. A review concerning diagnosis, clinical course and treatmen
t of this condition is presented.