Citation
A. Ata et Rg. Kerr, Elisabethamine: a new diterpene alkaloid from Pseudopterogorgia elisabethae, TETRAHEDR L, 41(31), 2000, pp. 5821-5825
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039
→ ACNP
Volume
41
Issue
31
Year of publication
2000
Pages
5821 - 5825
Database
ISI
SICI code
0040-4039(20000729)41:31<5821:EANDAF>2.0.ZU;2-Q
Abstract
Detailed chemical studies of the methanolic extract of Pseudopterogorgia el
isabethae, collected from the Florida Keys, have resulted in the isolation
of elisabethamine (1), a new diterpene alkaloid. Its structure was establis
hed with the aid of extensive spectroscopic studies. Compound 1 exhibited c
ytotoxicity against lung and prostate cancer cell lines as determined by an
MITT assay. (C) 2000 Elsevier Science Ltd. All rights reserved.