K. Shirai et al., Electrochemical oxidation of 2,2,2-trifluoroethanol to trifluoroacetaldehyde 2,2,2-trifluoroethyl hemiacetal, TETRAHEDR L, 41(31), 2000, pp. 5873-5876
Electrochemical oxidation of 2,2,2-trifluoroethanol (1) gave trifluoroaceta
ldehyde 2,2,2-trifluoroethyl hemiacetal (2b), which was more reactive than
commercially available trifluoroacetaldehyde ethyl hemiacetal (2a). The hig
h reactivity of 2b was utilized, for example, for the facile synthesis of 1
-furyl-2,2,2-trifluoroethanol (4) from furan. (C) 2000 Elsevier Science Ltd
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