Intramolecular sulfur-assisted NaBH4 reduction of esters synthesis of 5-oxo-ETE and 5-oxo-12-HETE

Authors
Khanapure, SP Saha, G Sivendran, S Powell, WS Rokach, J
Citation
Sp. Khanapure et al., Intramolecular sulfur-assisted NaBH4 reduction of esters synthesis of 5-oxo-ETE and 5-oxo-12-HETE, TETRAHEDR L, 41(30), 2000, pp. 5653-5657
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
30
Year of publication
2000
Pages
5653 - 5657
Database
ISI
SICI code
0040-4039(20000722)41:30<5653:ISNROE>2.0.ZU;2-4
Abstract
Ester groups are reduced very efficiently in sulfur-containing molecules si tuated at close proximity to the eater group. We have used this procedure t o regioselectively, efficiently and in high yield reduce an ester group in the presence of another ester group further removed from the sulfur atom. ( C) 2000 Elsevier Science Ltd. All rights reserved.