The functional activity of blood lymphocytes and neutrophils in bulls with
persistent cutaneous papillomatosis was evaluated. During clinical manifest
ation of papillomatosis, a blastogenic response of lymphocytes to T-cell mi
togens significantly decreased. In the regression period of papillomas grad
ual elevation of lymphocytic activity was found out and, at the end of eval
uation it was comparable with activity of lymphocytes in control animals. T
he phagocytic activity of neutrophils in affected animals was not significa
ntly altered in comparison with that in control animals. We demonstrated si
milar findings by evaluation of leukocyte, neutrophil and lymphocyte counts
.