Multinodular goiter and parotid carcinoma: a new case of Cowden's disease

Authors
Kacem, M Zili, J Zakhama, A Youssef, FH Mahjoub, S Boubakri, C El May, M
Citation
M. Kacem et al., Multinodular goiter and parotid carcinoma: a new case of Cowden's disease, ANN ENDOCR, 61(2), 2000, pp. 159-163
Citations number
31
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
ANNALES D ENDOCRINOLOGIE
ISSN journal
00034266 → ACNP
Volume
61
Issue
2
Year of publication
2000
Pages
159 - 163
Database
ISI
SICI code
0003-4266(200005)61:2<159:MGAPCA>2.0.ZU;2-H
Abstract
Cowden's Disease is an autosomal dominant genodermatosis associated with ab normalities of the breast, thyroid gland, gastrointestinal tract. We describe a 23-year-old girl who was diagnosed with this disease when she consulted for evaluation of a multinodular goiter. Further investigations revealed breast lesions, gastric polyposis and parotid cancer. Recognizing Cowden's disease is important for prompt screening for malignan cies. Skin lesions are markers of precancerous development.