The synthesis and antioxidant activity of azole derivatives of hemin

Citation
Ea. Rozhkova et al., The synthesis and antioxidant activity of azole derivatives of hemin, BIOORG KHIM, 26(6), 2000, pp. 466-470
Citations number
17
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANICHESKAYA KHIMIYA
ISSN journal
01323423 → ACNP
Volume
26
Issue
6
Year of publication
2000
Pages
466 - 470
Database
ISI
SICI code
0132-3423(200006)26:6<466:TSAAAO>2.0.ZU;2-Q
Abstract
New derivatives of proto- and deuterohemin IX containing tri- and tetrazole rings were synthesized and characterized. A pronounced antioxidant activit y was found for these compounds in the Fe(II)/ascorbate-dependent system of lipid peroxidation in murine liver homogenates.